ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy of laparoscopic Roux-en-Y gastric bypass (LRYGB) in the treatment of type 2 diabetes mellitus(T2DM).</p><p><b>METHODS</b>Clinical data of 62 cases undergoing LRYGB from May 2010 to October 2011 were analyzed retrospectively.</p><p><b>RESULTS</b>LRYGB was completed in 58 patients successfully. The mean operative time was(144.5±59.0) min and the mean intraoperative blood loss was(57.8±135.5) ml. Postoperatively two patients developed anastomotic bleeding, one gastric paralysis, one anastomotic leak, and one malnutrition, which were all healed by conservation treatment. One patient developed anastomotic stricture which was alleviated by balloon dilatation. Forty-nine cases were followed up for six months, in whom 34 patients required no further medical treatment, 9 received less medicines, and 6 were inactive. Body mass index, fasting C-peptide, and HbA1c were improved postoperatively. Compared to other patients, the 34 patients with clinical complete remission had higher BMI and shorter disease course(both P<0.05).</p><p><b>CONCLUSIONS</b>LRYGB can safely and efficiently be applied in T2DM patients. Short-term efficacy is satisfactory and the long-term outcomes require further evaluation.</p>
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Diabetes Mellitus, Type 2 , General Surgery , Gastric Bypass , Laparoscopy , Retrospective Studies , Treatment OutcomeABSTRACT
Laparoscopic Roux-en-Y gastric bypass (LRYGB) has become the gold standard operation for morbid obesity, because effects of LRYGB are quick and lasting. However, there are many potential risks due to the operative complexity and long learning curve. There are early and late complications after LRYGB. If the complications are not diagnosed and treated in time and correctly, serious results even death, may occur. Mortality after LRYGB is 0.87%. It is important for the continous and healthy development of LRYGB that postoperative complications can be diagnosed and managed in time and effectively.